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・ Small nucleolar RNA SNORD100
・ Small nucleolar RNA SNORD101
・ Small nucleolar RNA SNORD102
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・ Small nucleolar RNA SNORD105
・ Small nucleolar RNA SNORD110
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・ Small nucleolar RNA SNORD14
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Small nucleolar RNA SNORD19
・ Small nucleolar RNA SNORD20
・ Small nucleolar RNA SNORD21
・ Small nucleolar RNA SNORD22
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・ Small nucleolar RNA SNORD28
・ Small nucleolar RNA SNORD29
・ Small nucleolar RNA SNORD30
・ Small nucleolar RNA SNORD31
・ Small nucleolar RNA SNORD32
・ Small nucleolar RNA SNORD34


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Small nucleolar RNA SNORD19 : ウィキペディア英語版
Small nucleolar RNA SNORD19

SNORD19 (also known as HBII-108) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
SNORD19 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
HBII-108 is the human orthologue of the mouse MBII-108 and is predicted to guide 2'O-ribose methylation of the small subunit (SSU) ribosomal RNA (rRNA), 18S, on position G683.
In the human genome snoRNA HBII-108 is located in the introns of the gene nucleostemin (NS), along with another snoRNA HBII-210.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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